Shining a Light on Alport Syndrome

Shining a light on optogenetics

O ptogenetics is relatively new and has attracted much interest since the first publications from the field in the early 2000s. Both researchers and the media are fascinated by the notions it conjures of bionic implants. Notwithstanding potential applications, the technology has quickly become an important research tool in neuroscience with potential for developing a range of novel therapeutic ...

Shining a light on dark data.

1Chris Patil is at the Buck Institute for Age Research, Novato, California, USA 2Vivian Siegel is at the Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA (e-mails: [email protected]; [email protected]) Increasing the publication of dark data will require us to acknowledge and alter the incentives for multiple agents of action: journals, c...

Shining a light on the Sunshine Act.

Shining a light on growth cones

euronal growth cones have detergent-resistant membranes (DRMs), specialized cell membrane fractions enriched in GPI-anchored proteins and intracellular signaling molecules. But are the DRMs involved in regulating neurite outgrowth? Yes, say Nakai and Kamiguchi (page 1097), who developed a new technique for selectively disrupting DRMs, and used it to demonstrate the functional importance of thes...

Shining light on "Dark Winter".

On 22--23 June 2001, the Johns Hopkins Center for Civilian Biodefense Strategies, in collaboration with the Center for Strategic and International Studies, the Analytic Services Institute for Homeland Security, and the Oklahoma National Memorial Institute for the Prevention of Terrorism, held a senior-level exercise entitled "Dark Winter" that simulated a covert smallpox attack on the United St...